Total CE Credit Hours: 1
Course Info URL: https://www.ce-credit.com/courses/101775
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About the Course:
Objective: To assess preliminarily the effectiveness of acamprosate in binge eating disorder (BED).
Method: In this 10-week, randomized, placebo-controlled, flexible dose trial, 40 outpatients with BED received acamprosate (N = 20) or placebo (N=20). The primary outcome measure was binge eating episode frequency.
Results: While acamprosate was not associated with a significantly greater rate of reduction in binge eating episode frequency or any other measure in the primary longitudinal analysis, in the endpoint analysis it was associated with statistically significant improvements in binge day frequency and measures of obsessive- compulsiveness of binge eating, food craving, and quality of life. Among completers, weight and BMI decreased slightly in the acamprosate group but increased in the placebo group.
Conclusion: Although acamprosate did not separate from placebo on any outcome variable in the longitudinal analysis, results of the endpoint and completer analyses suggest the drug may have some utility in BED.
This course is based on the reading-based online article, Acamprosate in the Treatment Of Binge Eating Disorder: A Placebo-controlled Trial: International Journal of Eating Disorders; Volume 44, Issue 1 created by Anna L. Guerdjikova, Ph.D., Erin L. Winstanley, Ph.D., Anne M. O’Melia, MD, Nicole Mori, CNP, Jessica McCoy, BA, Paul E. Keck Jr., MD, James I. Hudson, MD,ScD, and Susan L. McElroy, MD
Publication Date:January 2011
Course Material Authors
Course Material Authors authored the material only, and were not involved in creating this CE course. They are identified here for your own evaluation of the relevancy of the material this course is based on.
This course is recommended for Counselors, Psychologists, Social Workers and other mental health professionals who seek knowledge about the pharmacotherapy of binge eating disorder (BED).
After taking this course, you should be able to:
- Describe the rationale for testing acamprosate, a glutamate receptor modulator, in the treatment of binge eating disorder.
- Assess the major findings of the study.
- Identify the limitations of the study.
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