Depression and dementia are common incapacitating diseases in old age. The exact nature of the relationship between these conditions remains unclear, and multiple explanations have been suggested: depressive symptoms may be a risk factor for, a prodromal symptom of, or a coincidental finding in dementia. They may even be unrelated or only connected through common risk factors. Multiple studies so far have provided conflicting results. The objective of this review is to determine whether a systematic literature review can clarify the nature of the relation between depressive symptoms and dementia. Methods, results, and conclusions are presented.
This course is based on the reading-based online article, Depressive Symptoms in the Elderly- An Early Symptom of Dementia? A Systematic Review created by Wietse Wiels, MD, et al. in 2020.
Front. Pharmacol. Volume 11: Article 34 Feb 2020
Course Material Authors
Course Material Authors authored the material only, and were not involved in creating this CE course. They are identified here for your own evaluation of the relevancy of the material this course is based on.
Wietse Wiels, MD
Dr. Wiels is a neurologist affiliated with the Department of Neurology, Universitair Ziekenhuis Brussel, Brussels, Belgium and the Center for Neurosciences (C4N), Vrije Universiteit Brussel, Brussels, Belgium. He is particularly interested in movement disorders (such as Parkinson's or Huntington's Disease), functional or 'psychogenic' symptoms and neuropsychiatry, palliative care and Evidence Based Medicine (EBM). He also researches depression and dementia.
Chris Baeken, M.D., Ph.D.
Dr. Baeken is a psychiatrist whose main interests are within the neurobiological field of Affective Disorders affiliated with the Center for Neurosciences (C4N), Vrije Universiteit Brussel, Brussels, Belgium and the Department of Psychiatry, Universitair Ziekenhuis Brussel, Brussels, Belgium (among other affiliations). He utilizes brain-imaging paradigms (MRI, fMRI, (S)PET,….) with or without the combination of neuromodulation techniques, such as rTMS and tDCS to gain more insight in the underlying mechanisms of emotional brain processes in the ‘healthy’ as well as in the ‘mentally affected’ human brain
Sebastiaan Engelborghs, M.D., Ph.D.
Dr. Engelborghs is full professor of neurosciences and neurochemistry at University of Antwerp and director of the Reference Center of Biological Markers of Dementia (BIODEM) at Institute Born-Bunge/ University of Antwerp. He as well is full professor of neurology and neurosciences at VUB, co-director of the VUB Center for Neurosciences (C4N) and chair of the department of neurology of the VUB university hospital, UZ Brussel. Sebastiaan Engelborghs is board certified in clinical neurology (2001) and neurological revalidation medicine (2009). Both clinically and with regard to research, he is specialized in neurodegenerative brain disorders that cause dementia.
Elizabeth Mosco, Ph.D. is a licensed psychologist in Reno, NV. She opened a private practice
after 10 years of conducting home-based assessment and therapy with the VA Sierra Nevada
Health Care System. Dr. Mosco’s clinical interests include maternal mental health, older adults,
and third wave cognitive behavioral therapies.
Counselors, marriage and family therapists, psychologists and social workers. This course is appropriate for all levels of knowledge.
After taking this course, you should be able to:
Recognize the leading hypotheses regarding the relationship between depression and dementia.
Describe the results of at least 2 research studies evaluating the relationship between depression and dementia.
Summarize the conclusions from this study regarding the relationship between depression and dementia.
Disclosure to Learners
Disclosure of Relevant Financial Relationships
CE Learning Systems adheres to the ACCME's Standards for Integrity and Independence in Accredited
Continuing Medical Education. Any individuals in a position to control the content of a CE activity –
including faculty, planners, reviewers, or others ― are required to disclose all relevant financial
relationships with ineligible entities (formerly known as commercial interests).
The following relevant financial relationships have been disclosed by this activity's planners, faculty, and
Planners and Reviewers
The planners of this activity have reported that they have no relevant financial relationships.
Faculty: Elizabeth Mosco, Ph.D., PMH-C, CPLC
No relevant financial relationships.
There is no commercial support for this distance-learning course.
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