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Anxiety, Irritability, and Agitation As Indicators of Bipolar Mania With Depressive Symptoms: a Post Hoc Analysis of Two Clinical Trials

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About the Course:

Bipolar I disorder is a mental health disorder consisting of more than just two distinct poles. Specifically, between the extremes of mania and depression, individuals can also experience mixed states in which various manic and depressive symptoms are present simultaneously. Symptoms common between both depression and mania include anxiety, irritability, and agitation (AIA). This manuscript focuses on a post-hoc study examining whether the presence of AIA symptoms are predictive of depression and/or prognosis.

This course is based on the article, Anxiety, Irritability, and Agitation as Indicators of Bipolar Mania with Depressive Symptoms: a post hoc analysis of two clinical trials created by Trisha Suppes, MD, PhD, et al. in 2017.

Publication Date:

Int Journal of Bipolar Disorders, 5(36) 2017

Course Material Authors

Trisha Suppes, MD, PhD

Dr. Suppes is a professor at Stanford University. She has published over 150 articles and presented at multiple conferences.

Jonas Eberhard, PhD

Dr Eberhard is an Associate Professor at Lund University and has published more than 40 articles on a variety of physical and behavioral health issues.

Ole Lemming, MSc

Ole Lemming works in biostatistics and is an employee of H. Lundbeck A/S (commonly known simply as Lundbeck) is a Danish international pharmaceutical company. Ole has published 16 articles in peer reviewed journals.

Course Creator

Jennifer Henderson

Dr. Henderson completed her PhD in clinical psychology at the Uniformed Services University of Health Sciences in Bethesda MD, and my internship at Wilford Hall Ambulatory Medical Center in San Antonio TX. She is am an integrative therapist who focuses on brief, positive, solutions-focused therapy and is experienced in treating a variety of mental health concerns— depression, anxiety, stress, grief, trauma, parenting concerns, and more. She is currently practicing in Alaska.

Recommended For:

This course is recommended for health care professionals, especially psychologists, counselors, social workers, and addiction counselors who seek knowledge about Bipolar disorder. It is appropriate for intermediate or higher levels of participants’ knowledge. This content is at an intermediate level.

Course Objectives:

  1. Discuss the history and clinical aspects of Bipolar I disorder with mixed states.

  2. Discuss the clinical importance of anxiety, irritability, and agitation (AIA) symptoms as they pertain to Bipolar I disorder.

  3. Describe the findings of the of the Suppes et al. (2017) study.

Course Material

References begin on page 10.

Course Material

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Course Retired
Course Number 102315
1 credit hour
Log in for credit hours relevant to your licensure.

  • Reading-Based Online
Exam Fee: No Longer Available

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4.43 out of 5
109 members have taken this course

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