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Alzheimer Disease Biomarkers, Attentional Control and Semantic Memory Retrieval: Synergistic and Mediational Effects of Biomarkers on a Sensitive Cognitive Measure

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About the Course:

Considerable research has focused on cognitive performance characteristics which can best discriminate healthy aging from the earliest stages of Alzheimer disease. Of increasing importance is the identification of potential biomarkers that may help facilitate early detection of the disease. This study examined the utility of combining attentional control with semantic retrieval as a sensitive correlate of such biomarkers and used mediation analyses to examine possible mechanisms by which identified Alzheimer disease biomarkers influence cognition.

This course is based on the reading-based online, Alzheimer Disease Biomarkers, Attentional Control and Semantic Memory Retrieval: Synergistic and Mediational Effects of Biomarkers on a Sensitive Cognitive Measure created by Andrew Aschenbrenner, PhD and David Balota, PhD in 2015.

Publication Date:

Neuropsychology, 29(3) 2015

Course Material Authors

Andrew Aschenbrenner, PhD

Dr. Aschenbrenner is an Instructor of Neurology at Washington University in St. Louis School of Medicine. His work focuses on cognitive changes that occur in healthy aging, preclinical Alzheimer disease and very mild dementia of the Alzheimer type. He has published multiple articles and presented at several conferences.

David Balota, PhD

Dr. Balota is a Professor of Psychological & Brain Sciences and Neurology at Washington University in St. Louis. Professor Balota works on issues related to visual word recognition, semantic memory, priming on implicit memory tests, and attention systems that modulate performance within each of these domains. He investigates these phenomena within young adults, older adults, and individuals who have dementing illnesses such as senile dementia of the Alzheimer’s type. He has published multiple articles in this area.

Course Creator

Jennifer Henderson

Dr. Henderson completed her PhD in clinical psychology at the Uniformed Services University of Health Sciences in Bethesda MD, and my internship at Wilford Hall Ambulatory Medical Center in San Antonio TX. She is am an integrative therapist who focuses on brief, positive, solutions-focused therapy and is experienced in treating a variety of mental health concerns— depression, anxiety, stress, grief, trauma, parenting concerns, and more. She is currently practicing in Alaska.

Recommended For:

This course is recommended for health care professionals, especially psychologists, counselors, social workers, and addiction counselors who seek knowledge about Alzheimer’s disease. This content is at the advanced level and this course is appropriate for participants with intermediate or advanced levvel of knowledge.

Course Objectives:

  1. Identify at least three of the biomarkers for the prodromal stage of Alzheimer’s disease.

  2. Describe at least 2 of the biomarkers associated with cognitive changes secondary to Alzheimer’s disease.

  3. Identify 2 neuropsychological instruments useful in measuring cognitive functioning.

  4. Discuss the salient results from this study.

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Course Material

References begin on page 17.

Exam Questions

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Course Number 102314
2 credit hours
Log in for credit hours relevant to your licensure.

  • Reading-Based Online
Exam Fee: $11.94 No exam fee with a membership package!
4.17 out of 5
38 members have taken this course