Total CE Credit Hours: 1
Course Info URL: https://www.ce-credit.com/courses/101374
About the Course:
To estimate the familiality and heritability of binge eating disorder (BED).
We used a new ACE structural equation model to estimate heritability from a case-control family study of BED conducted in the Boston area. The sample consisted of 150 overweight/obese probands with lifetime BED by DSM-IV criteria, 150 overweight/obese probands without lifetime BED, and 888 of their first-degree relatives. We compared our findings with those from a study of binge eating (in the absence of compensatory behaviors) among 7,831 Norwegian twins.
The prevalence of BED differed by sex and by age. In the case-control family study, BED was found to aggregate in families, and heritability was estimated as 57% (CI: 30-77%). Including shared environment did not substantially improve the model’s fit, nor did allowing sex-specific heritability. Findings from the twin study were similar.
BED appears to aggregate in families and have a significant genetic component.
This course is based on the reading-based online article, Familiality and Heritability of Binge Eating Disorder: Results of a Case-Control Family Study and a Twin Study: Provided by International Journal of Eating Disorders created by Kristin N. Javaras, PhD, Nan M. Laird, PhD, Ted Reichborn-Kjennerud, MD, Cynthia M. Bulik, PhD, Harrison G. Pope Jr, MD, and James I. Hudson, MD, ScD
International Journal of Eating Disorders/Wiley InterScience
March 2008, Volume 41, Issue 2
Course Material Authors
This course is recommended for health care professionals, especially psychologists, counselors, social workers, addiction counselors, officers of the court, and nurses who seek knowledge about suicidal behavior in adolescents. It is appropriate for all levels of participants’ knowledge.
Explain that ACE models partition the variance of a trait into three sources: additive genetic effects (A), shared or common environment effects ©, and unique environment effects (E).
Recognize that ACE models, although most commonly used with twin data, can also be used with more general family data.
State whether binge eating disorder is heritable.
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